1 The two main factors which influence cancer are genetic and epigenetic. Continuing to smoke after treatment for oral cancer increases the risk of developing a second oral cancer. Approximately 70% of patients with oral cancer are heavy drinkers. The American Cancer Society couldn’t do what we do without the support of our partners. People who have had oral cancer have a higher risk of developing another oral cancer, especially if they continue to use tobacco or alcohol. American Cancer Society. Or write us. Oral sex and risk of oral cancer: a meta-analysis of observational studies. Individuals who smoke pipes or cigars experience a risk for oral cancer similar to that of the cigarette smoker. Become a volunteer, make a tax-deductible donation, or participate in a fundraising event to help us save lives. HPV types are given numbers. Some risk factors for oral cancer, such as being male or aging, are not preventable. The risk of these cancers is even higher in people who both smoke and drink alcohol, with the highest risk in heavy smokers and drinkers. It's also important for people who have been treated for oral cavity or oropharyngeal cancer to give up all oral tobacco products. All forms of tobacco increase the risk for this cancer, including cigarettes, cigars, pipes, bidis and smokeless tobacco (including chewing tobacco and snuff). The following factors have been linked with oral cancer, but there is not enough evidence to show they are known risk factors. Pipe smokers also have a higher risk of developing cancer in their lips. While oral cancer can affect anyone, there are several risk factors that increase the likelihood of its development. How common is oral cancer in nonsmokers. The common risk factors of the disease include: Tobacco Consumption. Risk factors for developing oral cancer One of the biggest risk factors for oral cancer is tobacco use. Precancerous conditions of the mouth include leukoplakia and erythroplakia. Epstein-Barr virus is a risk factor for nasopharyngeal cancer and cancer of the salivary glands. (National Cancer Institute) Symptoms. A weak immune system can be caused by certain diseases present at birth, the acquired immunodeficiency syndrome (AIDS), and certain medicines (such as those given after organ transplants). Apart from these factors, there are other various etiological factors that cause oral cancer. But in most cases, it is impossible to rank them with absolute certainty. Tobacco use of any kind, including cigarettes, cigars, pipes, chewing tobacco and snuff, among others 2. It's been suggested that long-term irritation of the lining of the mouth caused by poorly fitting dentures is a risk factor for oral cancer. Most often it affects the skin (usually as an itchy rash), but it sometimes affects the lining of the mouth and throat, appearing as small white lines or spots. Fanconi anemia is a rare genetic condition that affects the bone marrow so it can’t make enough red blood cells, white blood cells or platelets. Oral sex and human papilloma virus-related head and neck squamous cell cancer: a review of the literature. They can infect the sexual organs (the penis in men or the vulva, vagina and cervix in women), the rectum and the anus. It’s also important to follow recommended screening guidelines, which can help detect certain cancers early. Many types of HPV are spread through sexual contact, including oral sex. This is especially true for people who work in the sun for long periods of time, such as farmers. For reprint requests, please see our Content Usage Policy. 2017;93(1105):704-709. What does it take to outsmart cancer? Cancers of the oral cavity and oropharynx usually take many years to develop, so they're not common in young people. Others may be related to personal choices such as smoking, drinking, or diet. Tax ID Number: 13-1788491. Our team of expert journalists brings you all angles of the cancer story – from breaking news and survivor stories to in-depth insights into cutting-edge research. > References : 1. HPV is a group of more than 100 different types of related viruses. Cigarette smoking is a major cause of cancers of the oral cavity in the United States. Oral cancer can occur at any age, but people over the age of 45 are at higher risk. Infection with HPV-18 may also increase the risk. Clin Epigenetics. You can help reduce your risk of cancer by making healthy choices like eating right, staying active and not smoking. Overall survival may also be affected. April 2017. © 2021 American Cancer Society, Inc. All rights reserved. Risk Factors for Oral Cancer By Dorothy Anderson | January 8, 2021 | Comments Off on Risk Factors for Oral Cancer. If you want to take good care of your dental health by avoiding oral cancer’s risk factors, keep reading. Top 5 Risk Factors for Oral Cancer You know your dentist is looking for cavities during regular check-ups, but you may not realize your dentist can check for cancer at the same time. If you […] The use of tobacco and alcohol synergistically increase the risk of oral cancer. Risk Factors The use of tobacco and alcohol are the two most important risk factors for cancer of the mouth. An inherited, or genetic, condition is passed from parents to their children through genes. The risk is especially high for people with heavy alcohol and tobacco use. Risk factors are generally listed in order from most to least important. During this medical procedure, blood stem cells from a donor are used to replace bone marrow that has been destroyed by disease, chemotherapy, or radiation. However, some lifestyle factors that can reduce the risk of oral cancer … Oral cancer is a severe disease, which can cause serious complications like death. People with a weakened immune system have a higher risk of developing oral cancer, especially lip cancer. Using oral tobacco products for a long time is linked to a very high risk. A risk factor is anything that changes a person’s chance of getting a disease such as cancer. People who chew betel quid or areca nut have a higher risk of developing oral cancer, especially in the inner lining of the cheeks and lips. Oral Cavity (Mouth) and Oropharyngeal (Throat) Cancer, inherited defects (mutations) in certain genes. In the worldwide strategies to decrease … This may because the dentures rub on the gums and cause sores that may develop into a cancerous tumour. But risk factors don't tell us everything. It is often combined with tobacco and chewed for very long periods and this habit can start in childhood. The more you drink, the greater your risk. And research has shown that these cancers are becoming more common in younger people Tobacco is the leading cause of cancer worldwide 4 and a well-established risk factor for oral SCC. Patients may experience symptoms at an early age and may develop anemia or aplastic anemia. More research is needed to clarify the role of these factors for oral cancer. More men than women develop oral cancer, and it occurs more often in men of African descent. Smoking is a risk factor for many cancers. Accessed at www.cancer.gov/types/head-and-neck/patient/adult/lip-mouth-treatment-pdq on February 22, 2018. There is a higher risk of developing SCC in the head and neck region (including the mouth) if a first-degree family member (parent, sibling or child) has been diagnosed with SCC of the head and neck. Cancer Facts & Figures 2018. Some, such as your age or race, can’t be changed. Smoking or using tobacco products increases the risk of oral cancer, especially if combined with high alcohol consumption. It is interesting to note that even smokeless tobacco can lead to cancer of the cheeks, gums, and lips. At the American Cancer Society, we’re on a mission to free the world from cancer. Cancer is known to be potentially passed on from generation to generation. Most cases of oral cancer occurred in patients over the age of 60, though you are considered at greater risk when you reach age 55. Different cancers have different risk factors. Almost 50% of oral cancer patients have been noted to reach the final stages of the disease in hospitals and health care centres (Shrivastava et al., 2013). One of the types of cancers that many family caregivers worry about is oral cancer. Another risk factor is excessive exposure to the sun, especially from a young age. Tobacco is, probably, the most common risk factor for OC. This disease occurs mainly in middle-aged people. Learn more about these partnerships and how you too can join us in our mission to save lives, celebrate lives, and lead the fight for a world without cancer. What steps can you take to lessen your chances to developing oral cancer? In Southeast Asia, South Asia, and certain other areas of the world, many people chew betel quid, which is made up of areca nut (betel nut), spices, lime, and other ingredients. Many studies show that not eating enough vegetables and fruit increases the risk of developing oral cancer. These products are often linked with cancer of the lip if they sit on the lips. Dyskeratosis congenital is a genetic syndrome that can cause abnormal red blood cells, skin rashes and abnormal fingernails and toenails. Do you know the risk factors for oral cancer? These include: 1. Betel quid, or paan, is areca nut (the seed from the fruit of the oriental palm) and lime wrapped in a betel leaf. The American Cancer Society is a qualified 501(c)(3) tax-exempt organization. Excessive sun exposure to your lips 4. According to some studies, the risk of these cancers in heavy drinkers and smokers may be as much as 100 times higher than the risk in people who don’t smoke or drink. Alterations in oral bacterial communities are associated with risk factors for oral and oropharyngeal cancer. Study shows that it is possible to develop oral cancer even without smoking and drinking. Having a risk factor, or even many, does not mean that a person will get the disease. 2017;9:124. National Cancer Institute. This increases the risk of oral cancer, which can occur as early as 2 years after GVHD. 2. Studying this possible link is complicated by the fact that smokers and frequent drinkers (who already have an increased risk of these cancers) are more likely to use mouthwash than people who neither smoke nor drink. Using smokeless tobacco products is linked with cancer of the gums and inner lining of the cheeks and lips because the tobacco regularly touches these areas. Papillomas are not cancers, and are more commonly called warts. Registered charity: 118829803 RR 0001, Family history of squamous cell carcinoma (SCC), International Cancer Information Service Group, infection with human immunodeficiency virus (HIV) or having acquired immunodeficiency syndrome (AIDS). The habit is a very common one, especially on the Indian Sub-continent and Southeast Asia where it is responsible for 40% of oral cancers. Not having any risk factors doesn't mean that you won't get it, either. A weakened immune system It isn’t known whether or not the following factors are linked with oral cancer. The risk of oral cancer among people with Fanconi anemia is up to 500 times higher than the general population. Of your dental health by avoiding oral cancer, but people over the age of 60 risk factors of oral cancer the incidence. ( GVHD ) is a genetic syndrome that can be a behaviour, substance or condition a cancerous tumour )! 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